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Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin

Epileptic seizures are a common feature associated with inherited mitochondrial diseases. This study investigated the role of mitochondrial oxidative stress in epilepsy resulting from mitochondrial dysfunction using cross-bred mutant mice lacking mitochondrial manganese superoxide dismutase (MnSOD o...

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Detalhes bibliográficos
Main Authors: Liang, Li-Ping, Waldbaum, Simon, Rowley, Shane, Huang, Ting-Ting, Day, Brian J., Patel, Manisha
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418969/
https://ncbi.nlm.nih.gov/pubmed/22200564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.12.025
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