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HYPERPHOSPHORYLATION OF REPLICATION PROTEIN A IN CISPLATIN-RESISTANT AND -SENSITIVE HEAD AND NECK SQUAMOUS CELL CARCINOMA CELL LINES

BACKGROUND: Resistance to chemotherapy is a major limitation in the treatment of head and neck squamous cell carcinomas (HNSCCs), accounting for high mortality rates in patients. Here, we investigated the role of replication protein A (RPA) in cisplatin and etoposide resistance. METHODS: We used 6 p...

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Detalhes bibliográficos
Main Authors: Manthey, Karoline C., Glanzer, Jason G., Dimitrova, Diana D., Oakley, Greg G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418920/
https://ncbi.nlm.nih.gov/pubmed/19787780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.21234
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