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Mapping the Protein Interaction Network of the Human COP9 Signalosome Complex Using a Label-free QTAX Strategy

The COP9 signalosome (CSN) is a multi-subunit protein complex that performs critical roles in controlling diverse cellular and developmental processes. Aberrant regulation of the CSN complex has been shown to lead to tumorigenesis. Despite its biological significance, our current knowledge of the fu...

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Détails bibliographiques
Auteurs principaux: Fang, Lei, Kaake, Robyn M., Patel, Vishal R., Yang, Yingying, Baldi, Pierre, Huang, Lan
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418852/
https://ncbi.nlm.nih.gov/pubmed/22474085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.016352
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