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Mapping the Protein Interaction Network of the Human COP9 Signalosome Complex Using a Label-free QTAX Strategy

The COP9 signalosome (CSN) is a multi-subunit protein complex that performs critical roles in controlling diverse cellular and developmental processes. Aberrant regulation of the CSN complex has been shown to lead to tumorigenesis. Despite its biological significance, our current knowledge of the fu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fang, Lei, Kaake, Robyn M., Patel, Vishal R., Yang, Yingying, Baldi, Pierre, Huang, Lan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418852/
https://ncbi.nlm.nih.gov/pubmed/22474085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.016352
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