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Nucleocytoplasmic Transport: A Role for Nonspecific Competition in Karyopherin-Nucleoporin Interactions
Nucleocytoplasmic transport occurs through the nuclear pore complex (NPC), which in yeast is a ∼50 MDa complex consisting of ∼30 different proteins. Small molecules can freely exchange through the NPC, but macromolecules larger than ∼40 kDa must be aided across by transport factors, most of which be...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418842/ https://ncbi.nlm.nih.gov/pubmed/22357553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013656 |
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