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Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo
Many cargoes destined for nuclear import carry nuclear localization signals that are recognized by karyopherins (Kaps). We present methods to quantitate import rates and measure Kap and cargo concentrations in single yeast cells in vivo, providing new insights into import kinetics. By systematically...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064595/ https://ncbi.nlm.nih.gov/pubmed/17116750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608141 |
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