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Engineering lymph node homing of ex vivo–expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7

Natural killer (NK) cells have gained significant attention in adoptive immunotherapy for cancer. Consequently, novel methods of clinical-grade expansion of NK cells have emerged. Subsets of NK cells express a variety of chemokine receptors. However, to expand the scope of adoptively transferred NK...

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Autori principali: Somanchi, Srinivas S., Somanchi, Anitha, Cooper, Laurence J. N., Lee, Dean A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418772/
https://ncbi.nlm.nih.gov/pubmed/22498742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-389924
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