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Borrelia burgdorferi Harbors a Transport System Essential for Purine Salvage and Mammalian Infection

Borrelia burgdorferi is the tick-borne bacterium that causes the multistage inflammatory disease Lyme disease. B. burgdorferi has a reduced genome and lacks the enzymes required for de novo synthesis of purines for synthesis of RNA and DNA. Therefore, this obligate pathogen is dependent upon the tic...

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Autores principales: Jain, Sunny, Sutchu, Selina, Rosa, Patricia A., Byram, Rebecca, Jewett, Mollie W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418744/
https://ncbi.nlm.nih.gov/pubmed/22710875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00514-12
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