Host Response Signature to Staphylococcus aureus Alpha-Hemolysin Implicates Pulmonary Th17 Response

Staphylococcus aureus pneumonia causes significant morbidity and mortality. Alpha-hemolysin (Hla), a pore-forming cytotoxin of S. aureus, has been identified through animal models of pneumonia as a critical virulence factor that induces lung injury. In spite of considerable molecular knowledge of ho...

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Detalhes bibliográficos
Main Authors: Frank, Karen M., Zhou, Tong, Moreno-Vinasco, Liliana, Hollett, Brian, Garcia, Joe G. N., Bubeck Wardenburg, Juliane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418743/
https://ncbi.nlm.nih.gov/pubmed/22733574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00191-12
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