The strategy for enhancing temozolomide against malignant glioma

A combined therapy of the alkylating agent temozolomide (TMZ) and radiotherapy is standard treatment, and it improves the survival of patients with newly diagnosed glioblastoma (GBM). The DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT) removes the most cytotoxic lesions generated b...

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Bibliografski detalji
Glavni autori: Nakada, Mitsutoshi, Furuta, Takuya, Hayashi, Yutaka, Minamoto, Toshinari, Hamada, Jun-ichiro
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2012
Teme:
Oncology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418701/
https://ncbi.nlm.nih.gov/pubmed/22912934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00098
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