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Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity
BACKGROUND: Plasminogen activator inhibitor type 1 (PAI-1) is the primary inhibitor of urokinase type plasminogen activators (uPA) and tissue type plasminogen activators (tPA), which mediate fibrinolysis. PAI-1 is also involved in the innate immunity by regulating cell migration and phagocytosis. Ho...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418576/ https://ncbi.nlm.nih.gov/pubmed/22747686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-149 |
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