Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity

BACKGROUND: Plasminogen activator inhibitor type 1 (PAI-1) is the primary inhibitor of urokinase type plasminogen activators (uPA) and tissue type plasminogen activators (tPA), which mediate fibrinolysis. PAI-1 is also involved in the innate immunity by regulating cell migration and phagocytosis. Ho...

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Bibliografiske detaljer
Main Authors: Jeon, Hyejin, Kim, Jong-Heon, Kim, Jae-Hong, Lee, Won-Ha, Lee, Myung-Shik, Suk, Kyoungho
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418576/
https://ncbi.nlm.nih.gov/pubmed/22747686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-149
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