Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome

Recent clinical and experimental evidence suggests that endoplasmic reticulum (ER) stress contributes to the life-and-death decisions of β cells during the progression of type 1 and type 2 diabetes. Although crosstalk between inflammation and ER stress has been suggested to play a significant role i...

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Detalhes bibliográficos
Main Authors: Oslowski, Christine M., Hara, Takashi, O'Sullivan-Murphy, Bryan, Kanekura, Kohsuke, Lu, Simin, Hara, Mariko, Ishigaki, Shinsuke, Zhu, Lihua J., Hayashi, Emiko, Hui, Simon T., Greiner, Dale, Kaufman, Randal J., Bortell, Rita, Urano, Fumihiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418541/
https://ncbi.nlm.nih.gov/pubmed/22883234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.07.005
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