Dopamine D(2) Antagonist-Induced Striatal Nur77 Expression Requires Activation of mGlu5 Receptors by Cortical Afferents

Dopamine D(2) receptor antagonists modulate gene transcription in the striatum. However, the molecular mechanism underlying this effect remains elusive. Here we used the expression of Nur77, a transcription factor of the orphan nuclear receptor family, as readout to explore the role of dopamine, glu...

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Bibliografische gegevens
Hoofdauteurs: Maheux, Jérôme, St-Hilaire, Michel, Voyer, David, Tirotta, Emanuele, Borrelli, Emiliana, Rouillard, Claude, Rompré, Pierre-Paul, Lévesque, Daniel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Research Foundation 2012
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418524/
https://ncbi.nlm.nih.gov/pubmed/22912617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00153
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