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Characterization of an apical ceramide-enriched compartment regulating ciliogenesis

We show that in Madin–Darby canine kidney (MDCK) cells, an apical ceramide-enriched compartment (ACEC) at the base of primary cilia is colocalized with Rab11a. Ceramide and Rab11a vesicles isolated by magnetic sorting contain a highly similar profile of proteins (atypical protein kinase C [aPKC], Cd...

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Main Authors: He, Qian, Wang, Guanghu, Dasgupta, Somsankar, Dinkins, Michael, Zhu, Gu, Bieberich, Erhard
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418310/
https://ncbi.nlm.nih.gov/pubmed/22718902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-02-0079
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