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NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum
Nascent polypeptide-associated complex (NAC) was initially found to bind to any segment of the nascent chain except signal sequences. In this way, NAC is believed to prevent mistargeting due to binding of signal recognition particle (SRP) to signalless ribosome nascent chain complexes (RNCs). Here w...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418300/ https://ncbi.nlm.nih.gov/pubmed/22740632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-02-0112 |
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