NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum

Nascent polypeptide-associated complex (NAC) was initially found to bind to any segment of the nascent chain except signal sequences. In this way, NAC is believed to prevent mistargeting due to binding of signal recognition particle (SRP) to signalless ribosome nascent chain complexes (RNCs). Here w...

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Main Authors: Zhang, Ying, Berndt, Uta, Gölz, Hanna, Tais, Arlette, Oellerer, Stefan, Wölfle, Tina, Fitzke, Edith, Rospert, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418300/
https://ncbi.nlm.nih.gov/pubmed/22740632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-02-0112
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