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Targeted and Reversible Blood-Retinal Barrier Disruption via Focused Ultrasound and Microbubbles
The blood-retinal barrier (BRB) prevents most systemically-administered drugs from reaching the retina. This study investigated whether burst ultrasound applied with a circulating microbubble agent can disrupt the BRB, providing a noninvasive method for the targeted delivery of systemically administ...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418291/ https://ncbi.nlm.nih.gov/pubmed/22912733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042754 |
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