Binding of Translationally Controlled Tumour Protein to the N-Terminal Domain of HDM2 Is Inhibited by Nutlin-3

Translationally Controlled Tumour Protein (TCTP), a highly conserved protein present in all eukaryotic organisms, has a number of intracellular and extracellular functions including an anti-apoptotic role. TCTP was recently shown to interact with both p53 and HDM2, inhibiting auto-ubiquitination of...

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Main Authors: Funston, Garth, Goh, Walter, Wei, Siau Jia, Tng, Quah Soo, Brown, Christopher, Jiah Tong, Loh, Verma, Chandra, Lane, David, Ghadessy, Farid
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418249/
https://ncbi.nlm.nih.gov/pubmed/22912717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042642
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