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An iron sulfur cluster loop motif in the Archaeoglobus fulgidus uracil-DNA glycosylase mediates efficient uracil recognition and removal()

The Family 4 Uracil DNA glycosylase from the hyperthermophilic organism Archaeoglobus fulgidus (AFUDG) is responsible for the removal of uracil in DNA as the first step in the Base Excision Repair (BER) pathway. AFUDG contains a large solvent-exposed peptide region containing an alpha helix and loop...

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Detaylı Bibliyografya
Asıl Yazarlar: Engstrom, Lisa M., Partington, Olga A., David, Sheila S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418143/
https://ncbi.nlm.nih.gov/pubmed/22646210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3000462
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