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An iron sulfur cluster loop motif in the Archaeoglobus fulgidus uracil-DNA glycosylase mediates efficient uracil recognition and removal()
The Family 4 Uracil DNA glycosylase from the hyperthermophilic organism Archaeoglobus fulgidus (AFUDG) is responsible for the removal of uracil in DNA as the first step in the Base Excision Repair (BER) pathway. AFUDG contains a large solvent-exposed peptide region containing an alpha helix and loop...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418143/ https://ncbi.nlm.nih.gov/pubmed/22646210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3000462 |
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