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PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells

BACKGROUND: Effective cancer chemotherapy remains an important issue in cancer treatment, and signal transducer and activator of transcription-3 (Stat3) activation leads to cellular resistance of anticancer agents. Polymers are ideal vectors to carry both chemotherapeutics and small interfering ribo...

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Bibliografski detalji
Glavni autori: Su, Wen-Pin, Cheng, Fong-Yu, Shieh, Dar-Bin, Yeh, Chen-Sheng, Su, Wu-Chou
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418083/
https://ncbi.nlm.nih.gov/pubmed/22904633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S33666
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