Phase 1/2 Study of Everolimus in Advanced Hepatocellular Carcinoma

BACKGROUND: The phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway plays a critical role in the pathogenesis of hepatocellular carcinoma (HCC). We performed a single-arm, phase 1/2 study of everolimus in patients with advanced HCC. METHODS: Patients with histologically confirmed mea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhu, Andrew X., Abrams, Thomas A., Miksad, Rebecca, Blaszkowsky, Lawrence S., Meyerhardt, Jeffrey A., Zheng, Hui, Muzikansky, Alona, Clark, Jeffrey W., Kwak, Eunice L., Schrag, Deborah, Jors, Kathryn R., Fuchs, Charles S., Iafrate, A. John, Borger, Darrell R., Ryan, David P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417818/
https://ncbi.nlm.nih.gov/pubmed/21538343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26165
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