Phase 1/2 Study of Everolimus in Advanced Hepatocellular Carcinoma

BACKGROUND: The phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway plays a critical role in the pathogenesis of hepatocellular carcinoma (HCC). We performed a single-arm, phase 1/2 study of everolimus in patients with advanced HCC. METHODS: Patients with histologically confirmed mea...

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Detalhes bibliográficos
Main Authors: Zhu, Andrew X., Abrams, Thomas A., Miksad, Rebecca, Blaszkowsky, Lawrence S., Meyerhardt, Jeffrey A., Zheng, Hui, Muzikansky, Alona, Clark, Jeffrey W., Kwak, Eunice L., Schrag, Deborah, Jors, Kathryn R., Fuchs, Charles S., Iafrate, A. John, Borger, Darrell R., Ryan, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417818/
https://ncbi.nlm.nih.gov/pubmed/21538343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26165
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