β—Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB(1) or CB(2) receptors

BACKGROUND AND PURPOSE: The endocannabinoid system may regulate glial cell functions and their responses to pathological stimuli, specifically, Alzheimer's disease. One experimental approach is the enhancement of endocannabinoid tone by blocking the activity of degradative enzymes, such as fatt...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Benito, Cristina, Tolón, Rosa María, Castillo, Ana Isabel, Ruiz-Valdepeñas, Lourdes, Martínez-Orgado, José Antonio, Fernández-Sánchez, Francisco Javier, Vázquez, Carmen, Cravatt, Benjamin F, Romero, Julián
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2012
Aiheet:
Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417461/
https://ncbi.nlm.nih.gov/pubmed/22321194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01889.x
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