D-carnosine octylester attenuates atherosclerosis and renal disease in ApoE null mice fed a Western diet through reduction of carbonyl stress and inflammation

BACKGROUND AND PURPOSE: Lipoxidation-derived reactive carbonyl species (RCS) such as 4-hydroxy-2-nonenal (HNE) react with proteins to form advanced lipoxidation end products (ALEs), which have been implicated in both atherosclerosis and renal disease. L-carnosine acts as an endogenous HNE scavenger,...

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Bibliografische gegevens
Hoofdauteurs: Menini, Stefano, Iacobini, Carla, Ricci, Carlo, Scipioni, Angela, Fantauzzi, Claudia Blasetti, Giaccari, Andrea, Salomone, Enrica, Canevotti, Renato, Lapolla, Annunziata, Orioli, Marica, Aldini, Giancarlo, Pugliese, Giuseppe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2012
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Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417451/
https://ncbi.nlm.nih.gov/pubmed/22229552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01834.x
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