Amphiregulin exosomes increase cancer cell invasion

Autocrine, paracrine and juxtacrine are recognized modes of action for mammalian EGFR ligands that include EGF, TGF-α (TGFα), amphiregulin (AREG), heparin-binding EGF-like growth factor (HB-EGF), betacellulin, epiregulin and epigen. We identify a new mode of EGFR ligand signaling via exosomes. Human...

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Detalhes bibliográficos
Main Authors: Higginbotham, James N., Beckler, Michelle Demory, Gephart, Jonathan D., Franklin, Jeffrey L., Bogatcheva, Galina, Kremers, Gert-Jan, Piston, David W., Ayers, Gregory D., McConnell, Russell E., Tyska, Matthew J., Coffey, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417320/
https://ncbi.nlm.nih.gov/pubmed/21514161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.03.043
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