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A Novel Role for IFN-Stimulated Gene Factor 3(II) in IFN-γ Signaling and Induction of Antiviral Activity in Human Cells
Type I (e.g., IFN-α, IFN-β) and type II IFNs (IFN-γ) have antiviral, antiproliferative, and immunomodulatory properties. Both types of IFN signal through the Jak/STAT pathway to elicit antiviral activity, yet IFN-γ is thought to do so only through STAT1 homodimers, whereas type I IFNs activate both...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417313/ https://ncbi.nlm.nih.gov/pubmed/21178011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001359 |
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