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Roles for the Ubiquitin-Proteasome Pathway in Protein Quality Control and Signaling in the Retina: Implications in the Pathogenesis of Age-Related Macular Degeneration

The accumulation of damaged or postsynthetically modified proteins and dysregulation of inflammatory responses and angiogenesis in the retina/RPE are thought be etiologically related to formation of drusen and choroidal neovascularization (CNV), hallmarks of age-related macular degeneration (AMD). T...

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Detalhes bibliográficos
Main Authors: Shang, Fu, Taylor, Allen
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417153/
https://ncbi.nlm.nih.gov/pubmed/22521794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2012.04.001
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