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The SLCO1B1*5 Genetic Variant is Associated with Statin-Induced Side Effects
OBJECTIVES: Identify SNPs associated with mild statin-induced side effects. BACKGROUND: Statin-induced side effects can interfere with therapy. SNPs in cytochrome P450 enzymes impair statin metabolism; the reduced function SLCO1B1*5 allele impairs statin clearance and is associated with simvastatin-...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417133/ https://ncbi.nlm.nih.gov/pubmed/19833260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2009.04.053 |
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