Pharmacogenetic Predictors of Statin-Mediated Low-Density Lipoprotein Cholesterol Reduction and Dose Response

BACKGROUND: There is interindividual variation in low-density lipoprotein cholesterol (LDLc) lowering by statins and limited study into the genetic associations of the dose dependant LDLc lowering by statins. METHODS AND RESULTS: Five hundred nine patients with hyperlipidemia were randomly assigned...

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Detalhes bibliográficos
Main Authors: Voora, Deepak, Shah, Svati H., Reed, Carol R., Zhai, Jun, Crosslin, David R., Messer, Chad, Salisbury, Benjamin A., Ginsburg, Geoffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995295/
https://ncbi.nlm.nih.gov/pubmed/20031551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.108.795013
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