The Receptor for Advanced Glycation End-products (RAGE) Sustains Autophagy and Limits Apoptosis, Promoting Pancreatic Tumor Cell Survival

Activation of the induced receptor for advanced glycation endproducts (RAGE) leads to initiation of NF-κB and MAP kinase signaling pathways resulting in propagation and perpetuation of inflammation. RAGE knock out animals are less susceptible to acute inflammation and carcinogen induced tumor develo...

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Bibliographic Details
Main Authors: Kang, Rui, Tang, Daolin, Schapiro, Nicole E., Livesey, Kristen M., Farkas, Adam, Loughran, Patricia, Bierhaus, Angelika, Lotze, Michael T., Zeh, Herbert J.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417122/
https://ncbi.nlm.nih.gov/pubmed/19834494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.149
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