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Development of a Low Toxicity, Effective pDNA Vector Based on Non-covalent Assembly of Bioresponsive Amino-β-Cyclodextrin:Adamantane-Poly(vinyl alcohol)-Poly(ethylene glycol) Transfection Complexes
A host:guest-derived gene delivery vector has been developed, based on the self-assembly of cationic β-CD derivatives with a poly(vinyl alcohol)MW27kD (PVA) main chain polymer bearing poly(ethylene glycol)MW750 (PEG) or MW2000 PEG and acid-labile adamantane-modified (Ad) grafts through an acid-sensi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417082/ https://ncbi.nlm.nih.gov/pubmed/22551467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc2005158 |
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