L-asparaginase inhibits invasive and angiogenic activity and induces autophagy in ovarian cancer

Recent work identified L-asparaginase (L-ASP) as a putative therapeutic target for ovarian cancer. We suggest that L-ASP, a dysregulator of glycosylation, would interrupt the local microenvironment, affecting the ovarian cancer cell—endothelial cell interaction and thus angiogenesis without cytotoxi...

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Detalhes bibliográficos
Main Authors: Yu, Minshu, Henning, Ryan, Walker, Amanda, Kim, Geoffrey, Perroy, Alyssa, Alessandro, Riccardo, Virador, Victoria, Kohn, Elise C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416969/
https://ncbi.nlm.nih.gov/pubmed/22333033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01547.x
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