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Comparable Polyfunctionality of Ectromelia Virus- and Vaccinia Virus-Specific Murine T Cells despite Markedly Different In Vivo Replication and Pathogenicity

Vaccinia virus (VACV) stimulates long-term immunity against highly pathogenic orthopoxvirus infection of humans (smallpox) and mice (mousepox [ectromelia virus {ECTV}]) despite the lack of a natural host-pathogen relationship with either of these species. Previous research revealed that VACV is able...

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Bibliografiske detaljer
Main Authors: Hersperger, Adam R., Siciliano, Nicholas A., Eisenlohr, Laurence C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416331/
https://ncbi.nlm.nih.gov/pubmed/22532670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00038-12
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