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The Dominant-Negative Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR Increases the Efficacy of Rift Valley Fever Virus MP-12 Vaccine
Rift Valley fever virus (RVFV), belonging to the genus Phlebovirus, family Bunyaviridae, is endemic to sub-Saharan Africa and causes a high rate of abortion in ruminants and hemorrhagic fever, encephalitis, or blindness in humans. MP-12 is the only RVFV strain excluded from the select-agent rule and...
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Main Authors: | , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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American Society for Microbiology
2012
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416293/ https://ncbi.nlm.nih.gov/pubmed/22573861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00778-12 |
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