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Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy

Rift Valley fever virus (RVFV), which causes hemorrhagic fever, neurological disorders or blindness in humans, and a high rate abortion and fetal malformation in ruminants(1), has been classified as a HHS/USDA overlap select agent and a risk group 3 pathogen. It belongs to the genus Phlebovirus in t...

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Autors principals: Kalveram, Birte, Lihoradova, Olga, Indran, Sabarish V., Ikegami, Tetsuro
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308613/
https://ncbi.nlm.nih.gov/pubmed/22083261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3400
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