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Intermolecular Binding between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF-κB Activation
The forkhead-associated (FHA) domain recognizes phosphothreonine (pT) with high specificity and functional diversity. TIFA (TRAF-interacting protein with an FHA domain) is the smallest FHA-containing human protein. Its overexpression was previously suggested to provoke NF-κB activation, yet its exac...
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主要な著者: | , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Microbiology
2012
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416184/ https://ncbi.nlm.nih.gov/pubmed/22566686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00438-12 |
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