Intracytoplasmic Trapping of Influenza Virus by a Lipophilic Derivative of Aglycoristocetin

We report on a new anti-influenza virus agent, SA-19, a lipophilic glycopeptide derivative consisting of aglycoristocetin coupled to a phenylbenzyl-substituted cyclobutenedione. In Madin-Darby canine kidney cells infected with influenza A/H1N1, A/H3N2, or B virus, SA-19 displayed a 50% antivirally e...

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Hlavní autoři: Vanderlinden, Evelien, Vanstreels, Els, Boons, Eline, ter Veer, Wouter, Huckriede, Anke, Daelemans, Dirk, Van Lommel, Alfons, Rőth, Erzsébet, Sztaricskai, Ferenc, Herczegh, Pàl, Naesens, Lieve
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416158/
https://ncbi.nlm.nih.gov/pubmed/22740402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07032-11
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