Mammalian Innate Resistance to Highly Pathogenic Avian Influenza H5N1 Virus Infection Is Mediated through Reduced Proinflammation and Infectious Virus Release

Respiratory epithelial cells and macrophages are the key innate immune cells that play an important role in the pathogenesis of influenza A virus infection. We found that these two cell types from both human and pig showed comparable susceptibilities to initial infection with a highly pathogenic avi...

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Detalhes bibliográficos
Main Authors: Nelli, Rahul K., Dunham, Stephen P., Kuchipudi, Suresh V., White, Gavin A., Baquero-Perez, Belinda, Chang, Pengxiang, Ghaemmaghami, Amir, Brookes, Sharon M., Brown, Ian H., Chang, Kin-Chow
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416141/
https://ncbi.nlm.nih.gov/pubmed/22718824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00244-12
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