Mammalian Innate Resistance to Highly Pathogenic Avian Influenza H5N1 Virus Infection Is Mediated through Reduced Proinflammation and Infectious Virus Release

Respiratory epithelial cells and macrophages are the key innate immune cells that play an important role in the pathogenesis of influenza A virus infection. We found that these two cell types from both human and pig showed comparable susceptibilities to initial infection with a highly pathogenic avi...

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Bibliografiske detaljer
Main Authors: Nelli, Rahul K., Dunham, Stephen P., Kuchipudi, Suresh V., White, Gavin A., Baquero-Perez, Belinda, Chang, Pengxiang, Ghaemmaghami, Amir, Brookes, Sharon M., Brown, Ian H., Chang, Kin-Chow
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Cellular Response to Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416141/
https://ncbi.nlm.nih.gov/pubmed/22718824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00244-12
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