Analysis by Single-Gene Reassortment Demonstrates that the 1918 Influenza Virus Is Functionally Compatible with a Low-Pathogenicity Avian Influenza Virus in Mice

The 1918-1919 “Spanish” influenza pandemic is estimated to have caused 50 million deaths worldwide. Understanding the origin, virulence, and pathogenic properties of past pandemic influenza viruses, including the 1918 virus, is crucial for current public health preparedness and future pandemic plann...

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Detalhes bibliográficos
Main Authors: Qi, Li, Davis, A. Sally, Jagger, Brett W., Schwartzman, Louis M., Dunham, Eleca J., Kash, John C., Taubenberger, Jeffery K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416129/
https://ncbi.nlm.nih.gov/pubmed/22718825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00887-12
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