Beijing Sublineages of Mycobacterium tuberculosis Differ in Pathogenicity in the Guinea Pig

The Beijing family of Mycobacterium tuberculosis strains is part of lineage 2 (also known as the East Asian lineage). In clinical studies, we have observed that isolates from the sublineage RD207 of lineage 2 were more readily transmitted among humans. To investigate the basis for this difference, w...

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Bibliographic Details
Main Authors: Kato-Maeda, Midori, Shanley, Crystal A., Ackart, David, Jarlsberg, Leah G., Shang, Shaobin, Obregon-Henao, Andres, Harton, Marisabel, Basaraba, Randall J., Henao-Tamayo, Marcela, Barrozo, Joyce C., Rose, Jordan, Kawamura, L. Masae, Coscolla, Mireia, Fofanov, Viacheslav Y., Koshinsky, Heather, Gagneux, Sebastien, Hopewell, Philip C., Ordway, Diane J., Orme, Ian M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Clinical Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416080/
https://ncbi.nlm.nih.gov/pubmed/22718126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00250-12
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