Association of Polymorphisms of the Mu Opioid Receptor Gene with the Severity of HIV Infection and Response to HIV Treatment

BACKGROUND: Mu opioid receptor (OPRM1) ligands may alter expression of chemokines and chemokine receptors involved in penetration of human immunodeficiency virus (HIV) type 1 into the cell. We suggest that OPRM1 variants may affect the pathophysiology of HIV infection. METHODS: DNA samples from 1031...

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Autors principals: Proudnikov, Dmitri, Randesi, Matthew, Levran, Orna, Crystal, Howard, Dorn, Magdalena, Ott, Jurg, Ho, Ann, Kreek, Mary Jeanne
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415853/
https://ncbi.nlm.nih.gov/pubmed/22457278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis264
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