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Evolution of SH2 domains and phosphotyrosine signalling networks
Src homology 2 (SH2) domains mediate selective protein–protein interactions with tyrosine phosphorylated proteins, and in doing so define specificity of phosphotyrosine (pTyr) signalling networks. SH2 domains and protein-tyrosine phosphatases expand alongside protein-tyrosine kinases (PTKs) to coord...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415846/ https://ncbi.nlm.nih.gov/pubmed/22889907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0107 |
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