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Protein kinases display minimal interpositional dependence on substrate sequence: potential implications for the evolution of signalling networks
Characterization of in vitro substrates of protein kinases by peptide library screening provides a wealth of information on the substrate specificity of kinases for amino acids at particular positions relative to the site of phosphorylation, but provides no information concerning interdependence amo...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Royal Society
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415838/ https://ncbi.nlm.nih.gov/pubmed/22889908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0010 |
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