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Analysis of the -398C/T polymorphism in the perforin gene in oncohematological patients
BACKGROUND: Recently, single nucleotide polymorphisms (SNPs) were identified in the promoter region of the perforin gene (PRF1) and it was found that the -398T mutant allele is correlated with lower amounts of protein in circulating CD8(+) cytotoxic T lymphocytes. OBJECTIVE: The aim of this study wa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Associação Brasileira de Hematologia e Hemoterapia
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415754/ https://ncbi.nlm.nih.gov/pubmed/23049318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20110076 |
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