Analysis of the -398C/T polymorphism in the perforin gene in oncohematological patients

BACKGROUND: Recently, single nucleotide polymorphisms (SNPs) were identified in the promoter region of the perforin gene (PRF1) and it was found that the -398T mutant allele is correlated with lower amounts of protein in circulating CD8(+) cytotoxic T lymphocytes. OBJECTIVE: The aim of this study wa...

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Autores principales: Garcia, Fernanda Bernadelli, dos Reis, Rafaella Kizzy Inácio, da Silva, Lucas Emanuel Pinheiro, Moraes-Souza, Helio
Formato: Artigo
Lenguaje:Inglês
Publicado: Associação Brasileira de Hematologia e Hemoterapia 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415754/
https://ncbi.nlm.nih.gov/pubmed/23049318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20110076
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