Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer

Continued androgen receptor (AR) signaling is an established mechanism underlying castration-resistant prostate cancer (CRPC), and suppression of AR signaling remains a therapeutic goal of CRPC therapy. Constitutively active androgen receptor splice variants (AR-Vs) lack the AR ligand-binding domain...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hu, Rong, Lu, Changxue, Mostaghel, Elahe A., Yegnasubramanian, Srinivasan, Gurel, Meltem, Tannahill, Clare, Edwards, Joanne, Isaacs, William, Nelson, Peter S., Bluemn, Eric, Plymate, Stephen R., Luo, Jun
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415705/
https://ncbi.nlm.nih.gov/pubmed/22710436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3892
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы