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Targeting of Noncanonical Wnt5a Signaling by AP-1 Blocker Dominant-Negative Jun When It Inhibits Skin Carcinogenesis

The transcription factor AP-1 (activator protein-1) regulates a number of genes that drive tumor promotion and progression. While basal levels of AP-1 activity are important for normal cell proliferation and cell survival, overactivated AP-1–dependent gene expression stimulates inflammation, angioge...

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Hlavní autoři: Kang, Moon-IL, Baker, Alyson R., Dextras, Christopher R., Cabarcas, Stephanie M., Young, Matthew R., Colburn, Nancy H.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415668/
https://ncbi.nlm.nih.gov/pubmed/22893789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912448820
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