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A selective small molecule NF-κB inhibitor from a high-throughput cell based assay for “AP-1 hits”

NSC 676914 has been identified as a selective NF-κB inhibitor that does not inhibit cell proliferation. This compound was originally identified in a high-throughput cell based assay for AP-1 inhibitors using synthetic compound libraries and the NCI natural product repository. NSC 676914 shows activi...

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Detalhes bibliográficos
Main Authors: Kang, Moon-Il, Henrich, Curtis J., Bokesch, Heidi R., Gustafson, Kirk R., McMahon, James B., Baker, Alyson R., Young, Matthew R., Colburn, Nancy H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813146/
https://ncbi.nlm.nih.gov/pubmed/19258426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0811
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